Acarbose, a generic diabetes medication, significantly extended lifespan in NIA Interventions Testing Program mouse studies and is now used in longevity protocols.
BPC-157 is a synthetic peptide derived from gastric juice that accelerates healing, reduces inflammation, and supports gut health.
CJC-1295 is a GHRH analog peptide that elevates growth hormone and IGF-1 levels for muscle growth, fat loss, and anti-aging benefits.
Dihexa is a potent nootropic peptide that promotes synaptogenesis, boosts BDNF signaling, and shows potential for Alzheimer's disease and cognitive decline.
A review of the most promising emerging supplements of 2025, from Urolithin A and Taurine to 5-Amino-1MQ and MOTS-c backed by new longevity research.
Epithalon is a tetrapeptide developed by Russian scientists that activates telomerase, extends telomeres, and has shown lifespan extension in animal and human research.
GHRP-2 is a potent growth hormone secretagogue that stimulates GH release, supports muscle growth, and enhances recovery.
Humanin is a mitochondria-encoded peptide that protects cells from death, improves insulin sensitivity, and declines with age—making it a compelling longevity target.
Ipamorelin is a selective GH secretagogue peptide known for clean GH release without cortisol or prolactin spikes, ideal for recovery and anti-aging.
SS-31 (Elamipretide) is a mitochondria-targeted peptide that reduces oxidative stress, restores ATP production, and shows promise for aging and heart disease.
A landmark 2023 Science study revealed taurine as a longevity factor that declines with age and extends healthy lifespan in animals when supplemented.
TB-500 (Thymosin Beta-4) is a regenerative peptide that promotes systemic healing, reduces inflammation, and accelerates tissue repair.
Urolithin A activates mitophagy to clear damaged mitochondria, improving muscle strength, endurance, and longevity biomarkers in human clinical trials.