Artichoke Leaf Extract for Liver and Cholesterol
Artichoke leaf extract contains cynarin and luteolin that stimulate bile flow, reduce liver enzyme levels, and lower total cholesterol by 10-15% in RCTs.
February 27, 2026·6 min read
Choline for Liver Health: NAFLD Prevention and Fat Transport
Choline deficiency directly causes NAFLD by impairing VLDL assembly. Most Americans fall short of the 400-550mg adequate intake. Here is what you need to know.
February 27, 2026·6 min read
Cranberry for UTI Prevention: PACs vs Juice vs Capsules
Cranberry prevents UTIs through type A PACs, not vitamin C or acidity. 36mg daily is the evidence-based dose. Most juice products fall far short.
February 27, 2026·5 min read
D-Mannose for UTI Prevention: How It Works
D-mannose prevents E. coli from adhering to the bladder wall. At 2g/day it matched nitrofurantoin in a 308-person RCT with far fewer side effects.
February 27, 2026·5 min read
Glutathione for Liver Health: Direct and Indirect Approaches
IV glutathione has clear bioavailability; oral forms are poorly absorbed unless liposomal. NAC remains the most reliable way to raise intracellular liver glutathione.
February 27, 2026·6 min read
Milk Thistle (Silymarin) Complete Guide: Liver Protection Science
Silymarin protects the liver through antioxidant, anti-inflammatory, and anti-fibrotic pathways. Phytosome form has 4-10x better bioavailability. 420mg/day is the standard dose.
February 27, 2026·6 min read
Pumpkin Seed Oil for Bladder Control: Evidence Review
A 2014 Japanese RCT found pumpkin seed oil at 320mg/day reduced urinary frequency and nocturia in postmenopausal women with overactive bladder over 6 weeks.
February 27, 2026·6 min read
Sulforaphane for Liver Detoxification: Nrf2 and Phase 2 Enzymes
Sulforaphane activates Nrf2 to upregulate NQO1, GST, and other phase 2 enzymes. Broccoli sprout extract at 50-100mg daily provides the most reliable dose.
February 27, 2026·6 min read
Supplements for Alcoholic Liver Disease: Recovery Support
Thiamine, zinc, SAMe, silymarin, and TUDCA support liver recovery from alcohol-related damage, but are most effective alongside abstinence or substantial reduction.
February 27, 2026·5 min read
Supplements to Improve Bile Production and Flow
Poor bile production causes fat malabsorption, constipation, and fat-soluble vitamin deficiency. TUDCA, phosphatidylcholine, artichoke, and taurine all improve bile flow.
February 27, 2026·6 min read
Supplements Safe for Chronic Kidney Disease
CKD changes which supplements are safe. Here is what the evidence supports for vitamin D, omega-3, and B vitamins in chronic kidney disease.
February 27, 2026·4 min read
Supplements for Fatty Liver: Evidence-Based Protocol
Choline, vitamin E, berberine, omega-3, and silymarin each target a different mechanism in fatty liver disease. Here is how to build an evidence-based protocol.
February 27, 2026·5 min read
Supplements for Gallbladder Health
Phosphatidylcholine, TUDCA, artichoke extract, and vitamin C support gallbladder function and reduce gallstone formation risk through complementary mechanisms.
February 27, 2026·6 min read
Supplements for Hepatitis B and C Support
Silymarin, vitamin D, selenium, and zinc have evidence as adjunctive support in hepatitis B and C, but must be used alongside antiviral medical treatment.
February 27, 2026·6 min read
Supplements for Interstitial Cystitis: Bladder Lining Support
Quercetin, L-arginine, and glycosaminoglycan support target the mechanisms behind interstitial cystitis pain and urgency without systemic side effects.
February 27, 2026·5 min read
Supplements to Support Kidney Function
Astragalus, omega-3, CoQ10, and vitamin D have the strongest evidence for supporting kidney function and reducing proteinuria in early kidney disease.
February 27, 2026·5 min read
Supplements for Kidney Stones: Prevention by Stone Type
The right supplements for kidney stones depend on your stone type. Here is what the evidence says for oxalate, uric acid, and calcium phosphate stones.
February 27, 2026·4 min read
Liver Detox Supplements: What Actually Works
Real liver detoxification uses specific enzymatic pathways. NAC, TUDCA, milk thistle, B vitamins, and cruciferous vegetables support these mechanisms with evidence.
February 27, 2026·6 min read
Supplements for Liver Health: Comprehensive Evidence Review
Milk thistle, TUDCA, NAC, vitamin E, and choline each address different aspects of liver health. Here is the evidence for each and how to use them.
February 27, 2026·6 min read
Supplements for Liver Inflammation: Anti-Fibrotic Support
Silymarin, vitamin E, omega-3, NAC, and curcumin each target different aspects of liver inflammation and fibrosis progression. Here is the evidence for each.
February 27, 2026·5 min read
Supplements for Non-Alcoholic Fatty Liver Disease
Vitamin E, omega-3, berberine, silymarin, and choline each address different NAFLD mechanisms. The PIVENS trial established vitamin E as first-line supplement therapy.
February 27, 2026·5 min read
Supplements for Overactive Bladder: Natural Options
Pumpkin seed oil, magnesium, and soy isoflavones reduce overactive bladder urgency and frequency through distinct mechanisms. Here is the evidence.
February 27, 2026·5 min read
Phase 2 Liver Detoxification Supplements
Phase 2 liver detox uses specific enzymatic pathways to neutralize toxins. Sulforaphane, NAC, calcium D-glucarate, B vitamins, and glycine support each pathway.
February 27, 2026·6 min read
Supplements for Urinary Tract Health
D-mannose, cranberry PACs, probiotics, and vitamin C each work through different mechanisms to support urinary tract health and prevent recurrent UTIs.
February 27, 2026·5 min read
TUDCA for Liver Health: The Most Potent Liver Supplement
TUDCA reduces ER stress, protects mitochondria, and improves bile flow. NAFLD RCTs show histological improvement at 1750mg. Hepatotoxicity protection at 250-500mg.
February 27, 2026·6 min read